Public ownership evidence

Spyre Therapeutics, Inc. Common Stock (SYRE) Ownership Disclosures

Read SYRE insider transactions, institutional 13F filings and Congressional disclosures with report dates, public availability and original receipts.

As of 2026-10-03T01:31:15.000Z

Recent Form 4 activity

2026-10-032026-10-01King-Jones HeidyS2,600Not reported
2026-10-032026-10-01King-Jones HeidyS2,100Not reported
2026-10-032026-10-01King-Jones HeidyS7,228Not reported
2026-10-032026-10-01King-Jones HeidyS16,605Not reported
2026-10-032026-10-01King-Jones HeidyS400Not reported
2026-10-032026-10-01Turtle CameronS100Not reported
2026-10-032026-10-01Turtle CameronS4,990Not reported
2026-10-032026-10-01Turtle CameronS3,989Not reported
2026-10-032026-10-01Turtle CameronS2,638Not reported
2026-10-032026-10-01Turtle CameronS2,683Not reported
2026-10-032026-10-01Turtle CameronS600Not reported
2026-10-032026-10-01Burrows Scott LS229Not reported
2026-10-032026-10-01Burrows Scott LS3,071Not reported
2026-10-032026-10-01Burrows Scott LS2,100Not reported
2026-10-032026-10-01Burrows Scott LS1,500Not reported
2026-10-032026-10-01Burrows Scott LS600Not reported
2026-10-032026-09-30Burrows Scott LS17,500Not reported
2026-09-042026-09-02King-Jones HeidyS400Not reported
2026-09-042026-09-01King-Jones HeidyS400Not reported
2026-09-042026-09-01King-Jones HeidyS6,206Not reported
2026-09-042026-09-01King-Jones HeidyS16,548Not reported
2026-09-042026-09-01King-Jones HeidyS4,845Not reported
2026-09-042026-09-02Burrows Scott LS18,232Not reported
2026-09-042026-09-01Burrows Scott LS200Not reported
2026-09-042026-09-01Burrows Scott LS2,016Not reported
2026-09-042026-09-01Burrows Scott LS4,384Not reported
2026-09-042026-09-01Burrows Scott LS900Not reported
2026-09-042026-09-01Turtle CameronS400Not reported
2026-09-042026-09-01Turtle CameronS3,700Not reported
2026-09-042026-09-01Turtle CameronS8,400Not reported
2026-09-042026-09-01Turtle CameronS2,500Not reported
2026-08-112026-08-07Albers Jeffrey W.S10,000Not reported
2026-08-112026-08-07Albers Jeffrey W.S8,000Not reported
2026-08-112026-08-07Albers Jeffrey W.S5,000Not reported
2026-08-062026-08-03Burrows Scott LS100Not reported
2026-08-062026-08-03Burrows Scott LS2,300Not reported
2026-08-062026-08-03Burrows Scott LS5,100Not reported
2026-08-062026-08-03Turtle CameronS16Not reported
2026-08-062026-08-03Turtle CameronS1,392Not reported
2026-08-062026-08-03Turtle CameronS5,635Not reported
2026-08-062026-08-03Turtle CameronS7,157Not reported
2026-08-062026-08-03Turtle CameronS800Not reported

90-day public availability window, up to 50 records.

Recent institutional filing receipts

These are raw ticker-matched positions in recent 13F receipts, including amendments. They are not deduplicated current ownership totals. Open the manager profile to inspect its effective filing book.

VIRGINIA RETIREMENT SYSTEMS ET Al2026-03-312026-08-2627,550$1,389,622None
VIRGINIA RETIREMENT SYSTEMS ET Al2026-06-302026-08-2611,250$998,775None
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM2026-06-302026-08-2564,687$5,742,912None
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM2026-06-302026-08-255,742,912$64,687,000None
MERCER GLOBAL ADVISORS INC /ADV2026-06-302026-08-2071,145$6,316,253None
Ensign Peak Advisors, Inc2026-03-312026-08-19148,537$7,492,206None
Fulcrum Asset Management LLP2026-06-302026-08-192,114$190,598None
Empowered Funds, LLC2026-06-302026-08-182,731$242,458None
Seven Fleet Capital Management LP2026-06-302026-08-1813,300$1,180,774None
DARK FOREST CAPITAL MANAGEMENT LP2026-06-302026-08-155,192$460,946None
TORONTO DOMINION BANK2026-06-302026-08-15270$23,971None
SEI INVESTMENTS CO2026-06-302026-08-1513,941$1,237,682None
Aster Capital Management (DIFC) Ltd2026-06-302026-08-152,865$254,355None
ABS Investment Management LLC2026-06-302026-08-1589$186,438None
Rafferty Asset Management, LLC2026-06-302026-08-1536,767$3,264,174None
Susquehanna Portfolio Strategies, LLC2026-06-302026-08-1553,101$4,714,307None
Quarry LP2026-06-302026-08-152$178None
ADAR1 Capital Management, LLC2026-06-302026-08-15283,982$25,211,922None
Artia Global Partners LP2026-06-302026-08-154,000$355,120None
DIADEMA PARTNERS LP2026-06-302026-08-1515,000$1,331,700None
Paradigm Biocapital Advisors LP2026-06-302026-08-153,840,778$340,984,271None
Commodore Capital LP2026-06-302026-08-15846,786$75,177,661None
XTX Topco Ltd2026-06-302026-08-1550,483$4,481,881None
Aquatic Capital Management LLC2026-06-302026-08-1525,222$2,239,209None
CHARLES SCHWAB INVESTMENT MANAGEMENT INC2026-06-302026-08-15652,958$57,969,611None
Sixth Street Partners Management Company, L.P.2026-06-302026-08-15652,958$57,969,611None
IFG Advisory, LLC2026-06-302026-08-15161$14,294None
Neo Ivy Capital Management2026-06-302026-08-1514,551$1,291,837None
Diametric Capital, LP2026-06-302026-08-1510,000$887,800None
Caption Management, LLC2026-06-302026-08-15173,700$15,421,086Put
Caption Management, LLC2026-06-302026-08-1525,000$2,219,500Call
Caption Management, LLC2026-06-302026-08-1536,000$3,196,080None
OSAIC HOLDINGS, INC.2026-06-302026-08-152$178None
OSAIC HOLDINGS, INC.2026-06-302026-08-1518,144$1,610,649None
Schonfeld Strategic Advisors LLC2026-06-302026-08-1519,089$1,694,720None
Squarepoint Ops LLC2026-06-302026-08-15139,605$12,394,132None
Man Group plc2026-06-302026-08-157,714$684,849None
Trexquant Investment LP2026-06-302026-08-1567,007$5,948,881None
Maven Securities LTD2026-06-302026-08-1540,000$3,551,200None
MetLife Investment Management, LLC2026-06-302026-08-1543,316$3,845,594None
Engineers Gate Manager LP2026-06-302026-08-1538,474$3,415,722None
Venrock Adviser, LLC2026-06-302026-08-152,985,448$265,048,073None
JANE STREET GROUP, LLC2026-06-302026-08-152,830$251,247None
JANE STREET GROUP, LLC2026-06-302026-08-1579$7,014None
JANE STREET GROUP, LLC2026-06-302026-08-1521,300$1,891,014Put
JANE STREET GROUP, LLC2026-06-302026-08-1541,300$3,666,614Call
Cormorant Asset Management, LP2026-06-302026-08-15225,000$19,975,500None
EVENTIDE ASSET MANAGEMENT, LLC2026-06-302026-08-15201,616$17,901,699None
Orion Porfolio Solutions, LLC2026-06-302026-08-152,577$228,786None
BOOTHBAY FUND MANAGEMENT, LLC2026-06-302026-08-156,453$572,897None

90-day public filing window, up to 50 source positions.

Recent Congressional disclosures

No records are available for this view.

Bounded public source preview, up to 25 disclosed events.

How to read the disclosure dates

The tables report different things: insider transactions, institutional positions and Congressional transaction ranges. Read each table with its source dates and units. They cannot be added into a combined ownership percentage.

  1. Company insiders

    SEC Form 4 purchases, sales and awards report transactions and their public filing availability.

  2. Institutional managers

    13F reports disclose delayed quarter-end positions. They are not a record of trades between quarters.

  3. Congressional filers

    Periodic transaction reports disclose transaction dates and amount brackets. Public filing dates determine what researchers could know.

Read the transaction codes

Awards use transaction code A, purchases P and sales S. An acquisition from an award is not the same as an open-market purchase. Joint filers may share a transaction. Use original receipts and availability dates to interpret the events.