Company research

Karyopharm Therapeutics Inc. (KPTI) stock fundamentals

Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases in the United States.

As of 2026-10-09

Exchange
XNAS
Sector
Healthcare
Industry
Biotechnology

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Daily valuation snapshot

Karyopharm Therapeutics Inc.: source evidence dated 2026-10-09.

Daily close (USD)
$0.61
Market capitalization (USD)
$13,722,283.3
Price / earnings (TTM)
Not reported
Price / book
Not reported
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Company overview

Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases in the United States. The company discovers, develops, and commercializes novel and small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead compound, include XPOVIO in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma; in combination with dexamethasone for the treatment of adult patients with relapsed or refractory multiple myeloma; and for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). It also developing Selinexor for treating hematological and solid tumor malignancies, including multiple myeloma, endometrial cancer, myelofibrosis, and DLBCL; and ELTANEXOR for treating Myelodysplastic Neoplasms, as well as verdinexor, KPT-9274, and IL-12 compounds. In addition, the company has license agreement with Menarini Group to develop and commercialize selinexor for human oncology indications; license agreement with Antengene Therapeutics Limited to develop and commercialize selinexor, eltanexor, and KPT-9274 for the treatment and/or prevention of human oncology indications, as well as verdinexor for the diagnosis, treatment, and/or prevention of human non-oncology indications; and distribution agreement for the commercialization of XPOVIO with FORUS Therapeutics Inc. Further, the company has a collaboration with Bristol Myers Squibb company to evaluate novel cereblon E3 ligase modulator agent mezigdomide in combination with Selinexor in patients with relapsed/refractory multiple myeloma. Karyopharm Therapeutics Inc. was incorporated in 2008 and is headquartered in Newton, Massachusetts.

Daily valuation snapshot

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These values come from the daily market snapshot dated 2026-10-09. TTM means trailing twelve months. Use the market date when comparing KPTI with another company.

Daily close (USD)$0.61
Market capitalization (USD)$13,722,283.3
Price / earnings (TTM)Not reported
Price / bookNot reported

Read KPTI's valuation metrics

  1. Company size

    Karyopharm Therapeutics Inc.'s recorded market capitalization is $13,722,283.3. It measures the market value of the company's equity, rather than its revenue or cash balance.

  2. Price relative to earnings

    P/E compares share price with trailing annual earnings per share. For a company with losses, inspect the earnings figures directly rather than treating a negative multiple as a cheap valuation.

  3. Price relative to book equity

    Price-to-book compares market equity value with recorded book equity. Intangible assets, profitability and the company's business affect how useful the comparison is.

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