SEC Form 13F

Paradigm Biocapital Advisors LP 13F Holdings

Inspect Paradigm Biocapital Advisors LP's 2026-06-30 SEC 13F positions, public filing date, amendments and original receipt.

As of 2026-08-15T03:59:59.999Z

Report period
2026-06-30
Publicly available
2026-08-15
Reported value
$5,340,558,034
Positions
28

Disclosed positions

REVOLUTION MEDICINES INCRVMDCOM$1,191,348,5716,361,323SHNone
NUVALENT INCNUVLCOM$731,667,4765,924,433SHNone
EDGEWISE THERAPEUTICS INCEWTXCOM$415,053,93710,215,455SHNone
GENMAB A/SGMABSPONSORED ADS$360,767,10913,133,131SHNone
SPYRE THERAPEUTICS INCSYRECOM NEW$340,984,2713,840,778SHNone
APOGEE THERAPEUTICS INCAPGECOM$209,233,5811,576,385SHNone
ORUKA THERAPEUTICS INCORKACOM$204,094,5392,144,526SHNone
TANGO THERAPEUTICS INCTNGXCOM$198,736,1696,357,523SHNone
BELITE BIO INCBLTESPONSORED ADS$189,844,5651,232,877SHNone
ERASCA INCERASCOM$174,956,0009,550,000SHNone
TARSUS PHARMACEUTICALS INCTARSCOM$174,699,3482,775,649SHNone
ALNYLAM PHARMACEUTICALS INCALNYCOM$144,494,400480,000SHNone
INSMED INCINSMCOM PAR $.01$141,375,6681,325,977SHNone
MBX BIOSCIENCES INCMBXCOM$138,442,4282,508,015SHNone
VAXCYTE INCPCVXCOM$123,692,0372,127,852SHNone
VIRIDIAN THERAPEUTICS INCVRDNCOM$123,515,9866,723,788SHNone
OLEMA PHARMACEUTICALS INCOLMACOM$108,468,9068,670,576SHNone
JADE BIOSCIENCES INCJBIOCOM NEW$63,491,5392,857,405SHNone
TYRA BIOSCIENCES INCTYRACOM$58,405,7081,828,607SHNone
ASSEMBLY BIOSCIENCES INCASMBCOM NEW$42,696,9951,553,748SHNone
EYEPOINT INCEYPTCOM NEW$41,332,6772,890,397SHNone
ACHIEVE LIFE SCIENCE INCACHVCOM$32,335,6204,951,856SHNone
VOR BIOPHARMA INCVORCOM NEW$32,217,5001,750,000SHNone
MAPLIGHT THERAPEUTICS INCMPLTCOM$24,580,936685,852SHNone
KARDIGAN INCKARDCOM$21,465,000900,000SHNone
LEXEO THERAPEUTICS INCLXEOCOM$19,436,4034,175,382SHNone
EDITAS MEDICINE INCEDITCOM$18,100,6655,586,625SHNone
INVENTIVA SAIVAADS$15,120,0004,000,000SHNone

Largest 50 positions by reported value; the filing may contain more positions.

How amendments affect these holdings

This view uses 1 effective filing version(s). A restatement replaces the previous book; a new-holdings amendment adds positions. 0 positions lack a resolved ticker and 0 positions are put or call entries.

A 13F is a delayed quarterly snapshot of disclosed holdings. It is not a complete trade ledger and does not reveal every position in a manager's portfolio. Option values refer to the reported underlying position rather than a traded option premium.

Quarter end and public filing date

Use the filing's public availability date when constructing a historical observation. The quarter-end report period is earlier and cannot be substituted for when the public learned the holdings.