SEC Form 13F

Palo Alto Investors LP 13F Holdings

Inspect Palo Alto Investors LP's 2026-06-30 SEC 13F positions, public filing date, amendments and original receipt.

As of 2026-08-20T03:59:59.999Z

Report period
2026-06-30
Publicly available
2026-08-20
Reported value
$723,718,198
Positions
52

Read this manager's filing book

Step 1 of 3

Disclosed positions

Palo Alto Investors LP: source evidence dated 2026-08-20T03:59:59.999Z.

Issuer
PTC THERAPEUTICS INC
Ticker
PTCT
Class
COM
Reported value
$74,950,268
Reported amount
918,846
Unit
SH
Option
None
What you should see

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Step 2 of 3

What was reported for this quarter?

13F positions are dated quarter-end holdings, with later publication and possible amendments. Read report period and availability before calling them current.

SEC 13F-HR/A: 0002073679-26-000102
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Open the effective filing receipt and inspect shares, value and any put/call classification separately.

Step 3 of 3

Browse institutional filings

Open the effective filing receipt and inspect shares, value and any put/call classification separately.

Browse institutional filings
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Disclosed positions

See the complete disclosed positions
PTC THERAPEUTICS INCPTCTCOM$74,950,268918,846SHNone
ACADIA PHARMACEUTICALS INCACADCOM$72,461,6292,864,096SHNone
INSMED INCINSMCOM PAR $.01$44,138,548413,980SHNone
MIRUM PHARMACEUTICALS INCMIRMCOM$40,834,953348,808SHNone
ANAPTYSBIO INCANABCOM$40,735,508603,489SHNone
BIOMARIN PHARMACEUTICAL INCBMRNCOM$39,068,500682,777SHNone
DYNE THERAPEUTICS INCDYNCOM$36,591,4411,647,521SHNone
UNITED THERAPEUTICS CORPUTHRCOM$33,911,51462,587SHNone
DISC MEDICINE INCIRONCOM$30,473,488416,646SHNone
BIOGEN INCBIIBCOM$30,308,681140,279SHNone
IOVANCE BIOTHERAPEUTICS INCIOVACOM$22,032,2295,296,209SHNone
ULTRAGENYX PHARMACEUTICAL INRARECOM$19,916,968596,495SHNone
NOVOCURE LTDNVCRORD SHS$19,398,6511,280,439SHNone
SYNDAX PHARMACEUTICALS INCSNDXCOM$18,908,594864,986SHNone
ANNEXON INCANNXCOM$16,833,5942,948,090SHNone
BICARA THERAPEUTICS INCBCAXCOM$16,341,614550,408SHNone
CAREDX INCCDNACOM$15,158,295531,870SHNone
CELLDEX THERAPEUTICS INCCLDXCOM NEW$14,878,642399,856SHNone
COMPASS THERAPEUTICS INCCMPXCOM$12,771,6705,831,813SHNone
ALKERMES PLCALKSSHS$12,708,931242,560SHNone
FIRST TRACKS BIOTHERAPEUTICSTRAXORD SHS$12,142,199603,489SHNone
PROTHENA CORP PLCPRTASHS$11,191,4871,143,155SHNone
TRAVERE THERAPEUTICS INCTVTXCOM$9,517,095167,525SHNone
TAYSHA GENE THERAPIES INCTSHACOM SHS$9,475,3111,391,382SHNone
ACLARIS THERAPEUTICS INCACRSCOM$8,535,0451,613,430SHNone
AGIOS PHARMACEUTICALS INCAGIOCOM$7,926,733213,601SHNone
CAPRICOR THERAPEUTICS INCCAPRCOM NEW$5,532,693229,763SHNone
ALIGN TECHNOLOGY INCALGNCOM$5,294,06931,389SHNone
ORUKA THERAPEUTICS INC - RestrictedORKACOM$3,192,57333,546SHNone
XENON PHARMACEUTICALS INCXENECOM$3,099,18451,345SHNone
NEUROCRINE BIOSCIENCES INCNBIXCOM$3,053,34918,117SHNone
EDWARDS LIFESCIENCES CORPEWCOM$3,043,07433,640SHNone
STOKE THERAPEUTICS INCSTOKCOM$2,769,12684,631SHNone
CYTOKINETICS INCCYTKCOM NEW$2,742,69232,195SHNone
PYXIS ONCOLOGY INCPYXSCOMMON STOCK$2,601,474864,277SHNone
EHEALTH INCEHTHCOM$2,209,3681,482,797SHNone
CRISPR THERAPEUTICS AGCRSPNAMEN AKT$2,160,05739,605SHNone
SAGIMET BIOSCIENCES INC-ASGMTCOM SER A$1,932,500250,000SHNone
NUVATION BIO INCNUVBCOM CL A$1,855,139326,609SHNone
BIONTECH SE-ADRBNTXSPONSORED ADS$1,825,08319,614SHNone
COMPASS PATHWAYS PLC ADRCMPSSPONSORED ADS$1,635,966115,616SHNone
HUMANA INCHUMCOM$1,582,9223,985SHNone
NEWAMSTERDAM PHARMA CO NVNAMSORDINARY SHARES$1,503,32744,359SHNone
VERASTEM INCVSTMCOM NEW$1,182,997309,685SHNone
MADRIGAL PHARMACEUTICALS INCMDGLCOM$959,5301,787SHNone
UROGEN PHARMA LTDURGNCOM$901,60024,500SHNone
BICYCLE THERAPEUTICS PLC-ADRBCYCSPONSORED ADS$856,014201,890SHNone
XERIS BIOPHARMA HOLDINGS INCXERSCOM$826,927104,410SHNone
ABEONA THERAPEUTICS INCABEOCOM NEW$672,786108,865SHNone
INSPIRE MEDICAL SYSTEMS INCINSPCOM$391,3198,772SHNone

Largest 50 positions by reported value; the filing may contain more positions.

How amendments affect these holdings

This view uses 1 effective filing version(s). A restatement replaces the previous book; a new-holdings amendment adds positions. 0 positions lack a resolved ticker and 0 positions are put or call entries.

A 13F is a delayed quarterly snapshot of disclosed holdings. It is not a complete trade ledger and does not reveal every position in a manager's portfolio. Option values refer to the reported underlying position rather than a traded option premium.

Quarter end and public filing date

Use the filing's public availability date when constructing a historical observation. The quarter-end report period is earlier and cannot be substituted for when the public learned the holdings.

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