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SEC Form 13F

BAKER BROS. ADVISORS LP 13F Holdings

Inspect BAKER BROS. ADVISORS LP's 2026-06-30 SEC 13F positions, public filing date, amendments and original receipt.

As of 2026-08-15T03:59:59.999Z

Report period
2026-06-30
Publicly available
2026-08-15
Reported value
$19,955,238,553
Positions
84
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Incyte CorporationINCYCOM$3,487,217,72930,762,330SHNone

First displayed source row from Disclosed positions. The full bounded history and coverage notes remain below.

The displayed observation date is 2026-06-30 and its public availability date is 2026-08-15. Subtracting those calendar dates gives 46 days of disclosure lag. Historical public research can use the record from the availability date, rather than backdating knowledge to the observation date. The calendar-day difference does not assert an intraday publication time.

Read the amount together with its Unit and Option columns. A reported put or call position is not an option premium paid, and a quarterly holding is not a purchase made on its public filing date. Check every accession in the effective amendment lineage below: a retained holding can originate in an earlier filing rather than the latest linked amendment.

Open the linked original receipts to verify the row, then inspect a second record before drawing a pattern. This public filing observation supplies source evidence, not a completed copy-trading return.

Disclosed positions

Inspect all 50 displayed rows: Disclosed positions

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Incyte CorporationINCYCOM$3,487,217,72930,762,330SHNone
BeOne Medicines Ltd.ONCSPONSORED ADS$2,508,182,5488,801,567SHNone
Revolution Medicines, Inc.RVMDCOM$2,143,111,89911,443,357SHNone
Madrigal Pharmaceuticals, Inc.MDGLCOM$1,150,754,1902,143,131SHNone
ACADIA Pharmaceuticals Inc.ACADCOM$1,085,696,47142,912,904SHNone
Kymera Therapeutics, Inc.KYMRCOM$992,725,9408,657,242SHNone
Insmed IncorporatedINSMCOM PAR $.01$937,841,3558,796,111SHNone
Celcuity Inc.CELCCOM$828,150,1597,915,792SHNone
Kodiak Sciences Inc.KODCOM$776,051,48719,919,186SHNone
Rhythm Pharmaceuticals, Inc.RYTMCOM$622,265,7475,604,483SHNone
Praxis Precision Medicines, Inc.PRAXCOM$586,953,1581,753,198SHNone
Alkermes plcALKSSHS$524,592,72910,012,267SHNone
Summit Therapeutics Inc.SMMTCOM$477,697,09032,786,348SHNone
GRAIL, Inc.GRALCOM$275,033,4784,028,614SHNone
AbCellera Biologics Inc.ABCLCOM$259,145,28333,012,138SHNone
Immunovant, Inc.IMVTCOM$209,419,0275,435,220SHNone
IDEAYA Biosciences, Inc.IDYACOM$186,723,8185,010,030SHNone
Kiniksa Pharmaceuticals International, plcKNSAORD SHS CL A$181,275,4202,834,643SHNone
Roivant Sciences Ltd.ROIVSHS$166,928,6494,716,831SHNone
Arrowhead Pharmaceuticals, Inc.ARWRCOM$162,431,7421,992,783SHNone
Ionis Pharmaceuticals, Inc.IONSCOM$162,364,2742,047,727SHNone
Edgewise Therapeutics, Inc.EWTXCOM$150,400,8433,701,719SHNone
Replimune Group, Inc.REPLCOM$122,271,87011,045,336SHNone
Nurix Therapeutics, Inc.NRIXCOM$113,016,5694,658,556SHNone
Stoke Therapeutics, Inc.STOKCOM$109,176,7263,336,697SHNone
Monte Rosa Therapeutics, Inc.GLUECOM$105,166,8114,345,736SHNone
Immatics N.V.IMTXSHS$96,321,7639,508,565SHNone
Denali Therapeutics Inc.DNLICOM$96,047,1223,734,336SHNone
Crinetics Pharmaceuticals, Inc.CRNXCOM$87,991,8202,351,465SHNone
Dianthus Therapeutics, Inc.DNTHCOM$83,068,947852,164SHNone
Structure Therapeutics Inc.GPCRSPONSORED ADS$76,883,8311,432,529SHNone
Celcuity Inc.CELCNote 2.75% 8/1/2031$69,158,68730,750,000PRNNone
Rapport Therapeutics, Inc.RAPPCOM$64,467,2401,547,090SHNone
Alumis Inc.ALMSCOM$56,631,7502,012,500SHNone
Prelude Therapeutics Inc.PRLDCOM$53,959,98210,123,824SHNone
Relay Therapeutics, Inc.RLAYCOM$52,889,1102,826,783SHNone
Mirum Pharmaceuticals, Inc.MIRMCOM$52,210,293445,975SHNone
Bicycle Therapeutics plcBCYCSPONSORED ADS$46,153,91410,885,357SHNone
Enliven Therapeutics, Inc.ELVNCOM$45,938,443905,191SHNone
Celldex Therapeutics, Inc.CLDXCOM$44,004,9551,182,611SHNone
Viridian Therapeutics, Inc.VRDNCOM$43,776,1692,383,025SHNone
Design Therapeutics, Inc.DSGNCOM$38,756,8822,678,430SHNone
Entrada Therapeutics, Inc.TRDACOM$37,335,2935,072,730SHNone
Faeth Therapeutics, Inc.FTHCOM$32,160,2751,286,411SHNone
Aktis Oncology, Inc.AKTSCOM$32,112,393996,351SHNone
Neurogene Inc.NGNECOM$31,188,682991,691SHNone
Jade Biosciences, Inc.JBIOCOM$27,340,0661,230,426SHNone
Taysha Gene Therapies, Inc.TSHACOM SHS$27,272,3884,004,756SHNone
Arcus Biosciences, Inc.RCUSCOM$26,045,677844,816SHNone
Disc Medicine, Inc.IRONCOM$25,573,913349,657SHNone

Largest 50 positions by reported value; the filing may contain more positions.

How amendments affect these holdings

This view uses 1 effective filing version(s). A restatement replaces the previous book; a new-holdings amendment adds positions. 2 positions lack a resolved ticker and 0 positions are put or call entries.

The displayed holdings combine the effective filing versions listed here. The latest receipt linked below identifies the current projection version; it is not proof that every retained holding originated in that latest amendment. Inspect all effective accessions when verifying a position's source.

A 13F is a delayed quarterly snapshot of disclosed holdings. It is not a complete trade ledger and does not reveal every position in a manager's portfolio. Option values refer to the reported underlying position rather than a traded option premium.

Effective SEC accessionRole in this view
0001104659-26-097191Latest effective version

Quarter end and public filing date

Use the filing's public availability date when constructing a historical observation. The quarter-end report period is earlier and cannot be substituted for when the public learned the holdings.