SEC Form 13F

PERCEPTIVE ADVISORS LLC 13F Holdings

Inspect PERCEPTIVE ADVISORS LLC's 2026-06-30 SEC 13F positions, public filing date, amendments and original receipt.

As of 2026-08-15T03:59:59.999Z

Report period
2026-06-30
Publicly available
2026-08-15
Reported value
$6,661,817,069
Positions
109

Read this manager's filing book

Step 1 of 3

Disclosed positions

PERCEPTIVE ADVISORS LLC: source evidence dated 2026-08-15T03:59:59.999Z.

Issuer
PRAXIS PRECISION MEDICINES I
Ticker
PRAX
Class
COM NEW
Reported value
$681,627,753
Reported amount
2,035,986
Unit
SH
Option
None
What you should see

The displayed owner or issuer and source fields identify the receipt to verify; keep reporting and availability dates separate.

Step 2 of 3

What was reported for this quarter?

13F positions are dated quarter-end holdings, with later publication and possible amendments. Read report period and availability before calling them current.

SEC 13F-HR: 0001012975-26-000777
What you should see

Open the effective filing receipt and inspect shares, value and any put/call classification separately.

Step 3 of 3

Browse institutional filings

Open the effective filing receipt and inspect shares, value and any put/call classification separately.

Browse institutional filings
What you should see

Keep reporting dates and units beside the answer, and inspect its original citations.

Disclosed positions

See the complete disclosed positions
PRAXIS PRECISION MEDICINES IPRAXCOM NEW$681,627,7532,035,986SHNone
SPYRE THERAPEUTICS INCSYRECOM NEW$383,484,8554,319,496SHNone
CELCUITY INCCELCCOM$334,491,0643,197,200SHNone
ASCENDIS PHARMA A/SASNDORD SHS$310,387,6651,163,721SHNone
RHYTHM PHARMACEUTICALS INCRYTMCOM$287,156,3342,586,295SHNone
ROIVANT SCIENCES LTDROIVSHS$286,144,4658,085,461SHNone
RELAY THERAPEUTICS INCRLAYCOM$263,926,75914,106,187SHNone
TRAVERE THERAPEUTICS INCTVTXCOM$213,183,7293,752,574SHNone
KARDIGAN INCKARDCOM$195,585,7888,200,662SHNone
NUVALENT INCNUVLCOM$195,192,3681,580,505SHNone
EDGEWISE THERAPEUTICS INCEWTXCOM$177,714,5644,373,974SHNone
APOGEE THERAPEUTICS INCAPGECOM$173,625,8381,308,113SHNone
AMYLYX PHARMACEUTICALS INCAMLXCOM$149,694,4818,334,882SHNone
MEIRAGTX HLDGS PLCMGTXCOM$145,727,74910,786,658SHNone
ORUKA THERAPEUTICS INCORKACOM$128,009,6461,345,063SHNone
INHIBRX BIOSCIENCES INCINBXCOM$122,963,0441,297,763SHNone
PROTAGONIST THERAPEUTICS INCPTGXCOM$120,358,728981,879SHNone
SOLID BIOSCIENCES INCSLDBCOM NEW$118,947,39311,906,646SHNone
ZYMEWORKS INCZYMECOM$109,342,3914,182,953SHNone
TANGO THERAPEUTICS INCTNGXCOM$105,565,0203,377,000SHNone
IMMATICS N.VIMTXSHS$105,184,40910,383,456SHNone
NURIX THERAPEUTICS INCNRIXCOM$104,813,4384,320,422SHNone
BIOCRYST PHARMACEUTICALS INCBCRXCOM$103,088,88010,308,888SHNone
REVOLUTION MEDICINES INCRVMDCOM$98,808,928527,600SHNone
AVALYN PHARMACEUTICALS INCAVLNCOM SHS$88,070,7442,675,296SHNone
MODERNA INCMRNACOM$70,030,0001,000,000SHPut
DYNE THERAPEUTICS INCDYNCOM$59,727,9092,689,235SHNone
BIOGEN INCBIIBCOM$59,669,938276,173SHNone
IMMUNOVANT INCIMVTCOM$52,299,9671,357,383SHNone
UNITEDHEALTH GROUP INCUNHCOM$48,548,078116,806SHNone
SPDR SERIES TRUSTXBIST STR SP BIOT$47,475,000300,000SHPut
IONIS PHARMACEUTICALS INCIONSCOM$44,878,140566,000SHNone
SUTRO BIOPHARMA INCSTROCOM SHS$43,320,8871,304,846SHNone
ALTO NEUROSCIENCE INCANROCOM SHS$42,485,0761,609,893SHNone
JAZZ PHARMACEUTICALS PLCJAZZSHS USD$40,964,900170,000SHNone
CORVUS PHARMACEUTICALS INCCRVSCOM$39,851,5692,667,441SHNone
SIONNA THERAPEUTICS INCSIONCOM$39,810,950905,000SHNone
CYTOMX THERAPEUTICS INC.CTMXCOM$39,146,94410,439,185SHNone
ARTIVION INCAORTCOM$39,036,9061,737,290SHNone
X4 PHARMACEUTICALS INCXFORCOM NEW$37,049,4037,933,491SHNone
CORCEPT THERAPEUTICS INCCORTCOM$34,639,576398,385SHNone
REPLIGEN CORPRGENCOM$33,866,045248,212SHNone
ANTERIS TECHNOLOGIES GLOBALAVRCOM$33,740,9393,425,476SHNone
RAPPORT THERAPEUTICS INCRAPPCOM$32,225,161773,342SHNone
DAMORA THERAPEUTICS INCDMRACOM NEW$31,810,2301,223,000SHNone
CHARLES RIV LABS INTL INCCRLCOM$31,750,600140,000SHNone
AXSOME THERAPEUTICS INC.AXSMCOM$28,993,007118,450SHNone
EYEPOINT INCEYPTCOM NEW$28,600,0002,000,000SHPut
DBV TECHNOLOGIES S ADBVTSPONSORED ADS$27,114,9401,653,350SHNone
IRHYTHM HOLDINGS INCIRTCCOM$26,616,966223,766SHNone

Largest 50 positions by reported value; the filing may contain more positions.

How amendments affect these holdings

This view uses 1 effective filing version(s). A restatement replaces the previous book; a new-holdings amendment adds positions. 3 positions lack a resolved ticker and 7 positions are put or call entries.

A 13F is a delayed quarterly snapshot of disclosed holdings. It is not a complete trade ledger and does not reveal every position in a manager's portfolio. Option values refer to the reported underlying position rather than a traded option premium.

Quarter end and public filing date

Use the filing's public availability date when constructing a historical observation. The quarter-end report period is earlier and cannot be substituted for when the public learned the holdings.

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