Company research

Denali Therapeutics Inc. Common Stock (DNLI) stock fundamentals

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor p

As of 2026-10-09

Exchange
XNAS
Sector
Healthcare
Industry
Biotechnology

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Daily valuation snapshot

Denali Therapeutics Inc. Common Stock: source evidence dated 2026-10-09.

Daily close (USD)
$19.45
Market capitalization (USD)
$3,109,031,988.35
Price / earnings (TTM)
Not reported
Price / book
3.72
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Company overview

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; DNL343 eIF2B activator program for amyotrophic lateral sclerosis; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Syndrome A); and DNL310 Tividenofusp alfa, an enzyme replacement therapy program for MPS II (Hunter Syndrome). Its Enzyme TransportVehicle (TV) programs include DNL952 for the treatment of Pompe disease; DNL111 for Parkinson's and Gaucher diseases; and DNL622 for Hurler syndrome (MPS I). The company's OTV programs also comprise DNL628 targeting tau for Alzheimer's disease; and DNL422 targeting alpha synuclein for Parkinson's disease, as well as antibody TV program includes DNL921 targeting Abeta for treating Alzheimer's disease. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.

Daily valuation snapshot

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These values come from the daily market snapshot dated 2026-10-09. TTM means trailing twelve months. Use the market date when comparing DNLI with another company.

Daily close (USD)$19.45
Market capitalization (USD)$3,109,031,988.35
Price / earnings (TTM)Not reported
Price / book3.72

Read DNLI's valuation metrics

  1. Company size

    Denali Therapeutics Inc. Common Stock's recorded market capitalization is $3,109,031,988.35. It measures the market value of the company's equity, rather than its revenue or cash balance.

  2. Price relative to earnings

    P/E compares share price with trailing annual earnings per share. For a company with losses, inspect the earnings figures directly rather than treating a negative multiple as a cheap valuation.

  3. Price relative to book equity

    DNLI's recorded price-to-book ratio is 3.72. That compares its market equity value with recorded book equity. Examine its business and balance sheet to understand why those values differ.

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