SEC Form 13F

Siren, L.L.C. 13F Holdings

Report period2026-06-30
Publicly available2026-08-14
Reported value$4,941,404,255
Positions117

Largest disclosed positions

IssuerTickerClassReported valueReported amount
Scholar Rock Holding CorpSRRKCOM$526,625,7159,575,013
Kymera Therapeutics IncKYMRCOM$336,651,6262,935,830
Erasca IncERASCOM$208,807,34811,397,781
Veradermics IncMANECOMMON STOCK$203,511,6801,655,374
Tango Therapeutics IncTNGXCOM$193,166,9196,179,364
Revolution Medicines IncRVMDCOM$168,552,000900,000
Bicara Therapeutics IncBCAXCOM$166,352,1795,602,970
Arrowhead Pharmaceuticals IncARWRCOM$139,828,4491,715,476
BeOne Medicines AGONCSPONSORED ADS$132,511,050465,000
Edgewise Therapeutics IncEWTXCOM$129,391,4763,184,629

Public filing evidence only. NexusTrade's simulated follower strategies are hypothetical, modeled results — not live trading returns and not investment advice.

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